Asthma Cure research and Clinical studies
The relationship of the bacteria Chlamydia pneumoniae and an Asthma CureAsthma Cure Research page
The trials, research and documentation below support the evidence of the relationship of asthma and the bacteria Chlamydia pneumoniae. There are hundreds of researchers around the globe studying the link between the bacteria Chlamydia pneumoniae as well as Mycoplasma pneumoniae and an asthma cure. Regardless of what you may have been told by your physician, many are being cured from asthma using information from these studies. Most don’t have the luxury to wait until these concepts are implemented into medical guidelines. When you can’t breathe and standard medical guidelines don’t provide practical solutions for your situation, then you have to consider all of the available options.
Use the information from these studies to convince your doctor to consider treating your severe asthma by understanding how asthma can be related to bacteria Chlamydia pneumoniae. Print several studies and results to present to your physician as doctors are usually very busy and probably won’t initially have the time to come to asthmastory.com and search through our articles.
Dr. Wilmore Webley Ph.D. (center) with fellow researchers in the lab of University of Massachusetts Amherst Dept. of Microbiology
Evaluation and management of acute bronchitis / 46
Hahn DL In: Hueston WJ, ed. 20 Common Problems in Respiratory Disorders. New York: McGraw-Hill, 2002; 141-153** Discussion of acute bronchitis and its potential role as a precursor to chronic respiratory illnesses such as asthma and COPD. [gview...
Host immune response to Chlamydia pneumoniae heat shock protein 60 is associated with asthma / 45
Huittinen T, Hahn D, Wahlstrom E, et al Eur Resp J 2001; 17:1078-1082*** In collaboration with Finnish researchers, the second report of an association of asthma with C. pneumoniae hsp60 antibodies, and the first to find that hsp60 antibodies were also related to...
Defining the relationship between Chlamydia pneumoniae and chronic asthma / 44
Hahn DL J Respir Dis 2000; 21:536* A brief commentary for practicing physicians, emphasizing the need for randomized, controlled treatment trials to further define the entity “chlamydial asthma”.
Intracellular Chlamydia pneumoniae infection demonstrated in alveolar epithelial and and Langhans giant cells in human lung / 43
Hahn DL, Kuo CC, Campbell LA Eur Respir J 2000; 16, Suppl 31:334s* As shown in animal models, this report documents that human lung alveolar epithelial cells and giant cells (macrophages) are targets for C. pneumoniae infection. (PDF Not available)
Failure of four and six weeks of treatment to eradicate evidence of Chlamydia pneumoniae from human lung and vascular tissue: pathology case reports / 42
Hahn D, Campbell LA, Kuo C-C. In: Saikku P, ed. Proceedings: Fourth Meeting of the European Society for Chlamydia Research. Helsinki, Finland: Esculapio, Bologna Italy, 2000; 395* Case reports suggesting the difficulty of eradicating persistent deep tissue C....
Serologic markers for Chlamydia pneumoniae in asthma / 40
Hahn DL, Peeling RW, Dillon E, et al Ann Allergy Asthma Immunol 2000; 84:227-233*** An example of an epidemiological association study of the association of C. pneumoniae antibodies with the “infectious asthma” syndrome (called AAWI in this study). An interesting...
Chlamydia pneumoniae antibodies and adult-onset asthma / 39
Hahn DL, Routes JM, Nelson HS J All Clin Immunol 2000; 106:404** Both diagnosis (via microbiologic isolation) and association (via epidemiological methods) have been used to study the role of infections in asthma. Diagnosis is appropriate in the study of individual...
Is there a role for antibiotics in the treatment of asthma? Involvement of atypical organisms / 38
Hahn DL Biodrugs 2000; 14:349-354** Review and discussion of evidence for antibiotic effectiveness in asthma, circa 2000.
The association of chronic cough with the risk of myocardial infarction: the Framingham Heart Study / 37
Hahn DL, McBride PE, Pasternak AV. Am J Med 2000; 108:179* Further discussion of the relationship between respiratory diseases (chronic cough, asthma, chronic bronchitis, and accelerated decline in lung function), heart disease, and C. pneumoniae infections. [gview...
Eradication of Chlamydia pneumoniae from bronchoalveolar lavage (BAL) fluid associated with asthma improvement: case report / 36
Hahn DL, Middleton KM, Campbell LA, et al Ann Allergy Asthma Immunol 1999; 84:115*** The first case report of post-antibiotic treatment eradication of C. pneumoniae from bronchoalveolar lavage fluid associated with lasting improvement in asthma symptoms, medication...
Chlamydia pneumoniae, asthma and COPD: what is the evidence? / 35
Hahn DL Immunol 1999; 83:271-292*** The most comprehensive review of the subject to date, introducing the concept that asthma and COPD may be related by development of lung remodeling caused by chronic C. pneumoniae infection. See Reference #54 for a more complete...
Chlamydia pneumoniae: a new possible cause of asthma / 33
Hahn DL, Allegra L. In: Allegra L, Blasi F, eds. Chlamydia pneumoniae: the lung and the heart. Milano: Springer-Verlag, Italia, 1999; 114-123 Review, circa 1999** Highlights of this review include case reports of documented C. pneumoniae infection associated with...
Chlamydia infection and pneumonia / 32
Kalayoglu MV, Hahn DL, Byrne GI In: Paradise LJ, Friedman H, Bendinelli M, eds. Opportunistic Intracellular Bacteria and Immunity. New York: Plenum Press, 1999; 233-253* A review of C. pneumoniae infection as a cause for pneumonia. See complementary review of C....
Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma / 31
Hahn D, Bukstein D, Luskin A, et al. Ann Allergy Asthma Immunol 1998; 80:45-49*** The first case series documenting long-lasting improvement in steroid-dependent (“brittle”) asthma after anti-chlamydial antibiotic treatment. [gview...
Can acute Chlamydia pneumoniae infection initiate chronic asthma? / 30
Hahn DL, McDonald R. Ann Allergy Asthma Immunol 1998; 81:339-344*** This ten-year prospective primary care study is the first to document that acute C. pneumoniae infections can cause acute wheezing illnesses (asthmatic bronchitis, pneumonia) that develop into chronic...
Chlamydia pneumoniae and asthma / 29
Blasi F, Allegra L, Tarsia P, et al Thorax 1998; 53:1095-1096* Discussion about a report of C. pneumoniae association with severe “brittle” asthma, but not with “ordinary” acute asthma exacerbations. A methodological concern was poor matching (by age and sex) of cases...
Detection of Chlamydia pneumoniae in abdominal aortic aneurysm specimens from patients with chronic obstructive pulmonary disease (COPD) and asthma: pilot results / 28
Hahn DL, Chang CK, Kuo C-C, et al In: Stephens RS, Byrne GI, Christiansen G, et al., eds. Proceedings of the Ninth International Symposium on Human Chlamydial Infection. Napa, California, USA: ISBN 0-9664383-0-2, 1998; 235-238*** Evidence for C. pneumoniae organism...
Age-dependent associations of acute vascular events with prior antibiotic prescriptions: implications for treatment trials of chlamydia-associated atherosclerosis / 27
Hahn DL, Werner NL In: Stephens RS, Byrne GI, Christiansen G, et al., eds. Proceedings of the Ninth International Symposium on Human Chlamydial Infection. Napa, California, USA: ISBN 0-9664383-0-2, 1998; 183-186** To investigate whether antibiotics are associated with...
Prevalence and persistence of Chlamydia pneumoniae antibodies in patients undergoing percutaneous transluminal angioplasty (PTCA) and associations with clinical disease severity / 26
Pasternak A, Hahn D, McBride P, et al. In: Stephens RS, Byrne GI, Christiansen G, et al., eds. Proceedings of the Ninth International Symposium on Human Chlamydial Infection. Napa, California, USA: ISBN 0-9664383-0-2, 1998; 179-182* Pilot study of C. pneumoniae...
Role of Chlamydia pneumoniae in acute respiratory tract infections, excluding pneumonias. Antibiotics for Clinicians / 25
Hahn DL (Supplement 3):9-18** Review of C. pneumoniae as a cause of acute non-pneumonic respiratory tract illnesses.
Intracellular pathogens and their role in asthma: Chlamydia pneumoniae in adult patients / 24
Hahn DL Eur Respir Rev 1996; 6:224-230** A second review of C. pneumoniae and asthma in adults.
Association of Chlamydia pneumoniae IgA antibodies with recently symptomatic Asthma / 23
Hahn DL, Anttila T, Saikku P. Epidemiol Infect 1996; 117:513-517*** Due to use of a polyvalent (mixed) antibody, the initial studies could not distinguish whether asthma was associated with C. pneumoniae IgG antibodies, IgA antibodies, or both. This study found that...
Incident wheezing and prevalent asthma have different serologic patterns of “acute” Chlamydia pneumoniae antibodies in adults / 22
Hahn DL In: Stary A, ed. Proceedings of the Third Meeting of the European Society for Chlamydia Research. Vienna, Austria: Società Editrice Esculapio, Bologna, 1996; 226** Addresses an important methodological issue surrounding interpretation of C. pneumoniae...
Evidence for Chlamydia pneumoniae infection in asthma / 21
Hahn DL In: Allegra L, Blasi F, eds. Chlamydia Pneumoniae Infection. Milan, Italy: Springer-Verlag, 1995; 65-75** The first of several reviews of current knowledge of C. pneumoniae and asthma. See also References #24, #33, #35 , #47 and especially #54 for more recent...