Chlamydia pneumoniae-Specific IgE Is Prevalent in Asthma and Is Associated with Disease Severity / 64

David L. Hahn 1, Allison Schure 2, Katir Patel 2, Tawanna Childs 2, Eduard Drizik 2, Wilmore Webley 2,
1 – Departments of family medicine, University of Wisconsin School of Medicine and Public Health, and the Dean Clinic, Madison Wisconsin
2 – Department of Microbiology, University of Massachuttes

PLoS ONE 2012; 7(4):1-9.***

This study found that half of community-based asthma patients had “allergic antibodies” directed against C. pneumoniae, and of these “allergic” asthmatics, 50% also had evidence for an active infection circulating in their blood. Also, being “allergic” to the bacteria was strongly associated with having more severe asthma. This finding adds to the growing body of evidence that C. pneumoniae infection may be involved in causing more severe asthma symptoms.

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