Host immune response to Chlamydia pneumoniae heat shock protein 60 is associated with asthma / 45

Huittinen T, Hahn D, Wahlstrom E, et al
Eur Resp J 2001; 17:1078-1082***
In collaboration with Finnish researchers, the second report of an association of asthma with C. pneumoniae hsp60 antibodies, and the first to find that hsp60 antibodies were also related to lower lung function. Chlamydial hsp60 is associated with scarring damage in tubal infertility and trachoma, suggesting the same process might be occurring in chronically infected human lung tissue to produce lung remodelling and COPD (see References #35 & #54).

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